Stage III Melanoma: Clinical Trial, Recovery and Hope
Nick's Story
Nick’s melanoma journey began with what seemed like a mosquito bite on his left forearm. After an early in-situ melanoma diagnosis in 2021, he later faced Stage III melanoma when a lump was found under his arm. Through clinical trial treatment, surgery, unexpected immune-related side effects and the steadfast support of his wife Melinda, family, friends and Melanoma Patients Australia, Nick’s story is one of gratitude, resilience and making the most of every day.
Life in Retirement With Family, Activity and Purpose
Nick lives in Perth with his wife, Melinda. Recently retired, the couple are enjoying a busy and active life filled with family, fitness, hobbies and volunteering.
Nick previously worked in the mining industry and veterinary field. He and Melinda have two daughters: Hayley, who is married to Michael and expecting their first grandchild, and Gillian, who lives in Melbourne and gives them a wonderful reason to visit often.
In retirement, Nick and Melinda walk, swim, snorkel, cycle and try to keep reasonably fit. They have also started playing golf, Melinda is learning piano, and Nick is learning the saxophone. They visit Melinda’s mother, who has advanced Alzheimer’s disease, play bridge, volunteer and treasure time with family.
A Melanoma Diagnosis That Began With an Itch
In 2021, Nick noticed what he thought was a mosquito bite on his left forearm. Two weeks later, it was still itchy. Melinda encouraged him to have it checked, and his GP arranged a biopsy.
The result was an in-situ melanoma. Nick and Melinda were relieved it had been found early. He underwent a wide area excision with a plastic surgeon, and the margins were clear.
Eighteen months later, Melinda noticed a lump under Nick’s left armpit. Tests showed it was a tumour in his lymph nodes. Fortunately, it had not spread further, but Nick was diagnosed with Stage III melanoma.
After doing extensive research, Nick was keen to join the global NADINA clinical trial, which offered neoadjuvant immunotherapy. Neoadjuvant treatment means immunotherapy is given before surgery rather than after it, and the trial showed promising long-term outcomes.
Clinical Trial Treatment and Surgery for Stage III Melanoma
Nick was grateful to be accepted into the NADINA clinical trial. He received two immunotherapy infusions, three weeks apart, before undergoing surgery to remove the lymph nodes in his armpit.
The treatment response was remarkable. The cancer had reduced by 97 per cent, and Nick did not need further treatment after surgery. As part of the clinical trial, he now has CT scans every three months for five years.
“I am so glad that due to the success of this trial, this type of treatment is available to anyone in Australia.”
Managing Side Effects and an Unexpected Immune Reaction
During treatment, Nick experienced minimal adverse reactions apart from some fatigue. He focused on exercise, eating well and staying as healthy as possible.
Eighteen months after surgery, however, Nick faced an unexpected immune-related reaction. His immune system began attacking his body, causing demyelination in his brainstem.
He initially experienced double vision, loss of balance, slower speech and slower thought processes. His taste and digestive system were also affected. Nick spent time in hospital, and steroid treatment helped reduce his symptoms.
Despite the challenges, Nick remains deeply grateful for his response to immunotherapy, the effectiveness of steroids, the support of loved ones and the medical advances that have helped him.
The Support of Family, Friends and Medical Care
Throughout his melanoma experience, Nick has been surrounded by strong support, especially from Melinda, who has been with him through appointments, treatment and recovery.
He is also grateful for the care of professional medical staff and for the progress made through medical research.
“I am so grateful for the amazing advancements medical research has made, and all the professional medical staff that have helped me.”
Finding Support Through Melanoma Patients Australia
When Nick was first diagnosed with Stage III melanoma, he contacted the Melanoma Patients Australia telehealth nurse. At a time when the path ahead felt complex and unfamiliar, that support helped him navigate the early stages of diagnosis and treatment.
Nick has since become the Group Support Facilitator for the Perth melanoma support group, helping to create a welcoming space for people affected by melanoma to connect, share experiences and feel less alone. The group meets in person and also offers hybrid options, making it easier for people to take part. For Nick, supporting others, especially those newly diagnosed, has become an important way to give back and continue raising awareness through Melanoma Patients Australia.
A Message of Hope and Awareness After Melanoma
Melanoma has changed Nick’s outlook on life. He is more focused on being grateful for each day and is committed to helping others whose lives have been affected by melanoma.
His message is simple: “Make the most of each day, enjoy family and friends.”
Nick’s story reflects the importance of listening to changes in your body, seeking medical advice early, accessing new treatment options where appropriate and leaning on support when melanoma becomes part of life.
Nick shared his story in December 2025. Melanoma Patients Australia thanks Nick for generously sharing his melanoma experience. We acknowledge the challenges faced by all Australians affected by melanoma and the strength shown by patients, carers and families every day.
Visit here for more information about clinical trials or for Melanoma Patients Australia Support Groups, register here.
If this story has raised questions or you are seeking support, contact the National Melanoma Support Line on 1300 884 450.
