Stage 3 melanoma is defined by the presence of lymph node involvement combined with the thickness and ulceration in the primary skin melanoma. There are four subclasses of Stage III Melanoma: IIIA, IIIB, IIIC, IIID. The subclasses relate to the size and number of glands that contain the melanoma cells. There is no evidence the cancer has spread to distant sites (metastasis).
