Chemotherapy is a systemic treatment (involving the whole body) which focuses on removing cancer cells by targeting rapidly dividing cells. Cancer cells as well as the cells of the digestive system, hair cells and other healthy cells are all rapidly dividing cells. Damage to healthy cells cause side effects including hair loss, nausea and fatigue.
DTIC is given to shrink or slow the growth of melanoma tumors that have spread throughout the body.
It is a chemotherapy drug, specifically an alkylating agent, that interferes with the growth of cancer cells.
Decarbazine is rarely used due to its poor response rates and significant side effects.